The #1 overall seed has won it twice since the expansion to 64, compared to the #2 overall seed winning it 3 times, the #3 seed winning it 3 times, the #4 seed winning it 1 time, the #5 seed winning it 3 times, etc.

There's no "curse" on the #1 overall seed, it's just a hard tournament to win (hard to go deep in) no matter who you are. And if we're the #1 overall seed, it means we had a really fun 4 months in the regular season.