It's very difficult for college teams to actually be really, really good at multiple comprehensive concepts. The amount of practice time and the versatility or roster depth necessary to be balanced between the run and pass is usually beyond most programs. You see this most prominently at tight end.

The best tight ends you've heard of are usually just okay run-blockers and great receivers. Then there are tight ends who are great blockers but aren't typically awesome receivers. The challenge of the pro-style spread is usually how to run the ball effectively from formations with a TE if the TE isn't actually a good run-blocker.